一、基本信息
刘代喜，女，博士，现任开云手机版登录入口助理研究员、硕士研究生导师。主要从事新型抗感染及抗肿瘤活性天然产物的发现及功能研究工作。
邮箱：liudaixi@sdu.edu.cn
二、教育及工作经历
2022.12-至今，开云手机版登录入口，助理研究员
2020.7-2022.11，山东大学海洋研究院，博士后
2016.09-2020.7，山东大学海洋研究院，海洋生物学，博士
三、研究方向
1）海洋蓝细菌来源的活性次级代谢产物挖掘及其生物合成途径研究；
2）药用动物来源的活性毒素多肽的发现及功能研究。
四、代表性论文
Liu Daixi#;Lv Haibo#; Wang Yafei#; Chen Jinyu; Li Dexin; Huang Ranran*; Selective RNA processing and stabilization are multi-layer and stoichiometric regulators of gene expression inEscherichia coli, Advanced Science, 2023, 2301459.
Liu Daixi;Chen Jinyu; Wang Yafei; Meng Yue; Li Yuanning; Huang Ranran; Xia Yongzhen; Liu Huaiwei; Jiao Nianzhi; Xun Luying; Liu Jihua*;Synechococcussp. PCC7002 uses Peroxiredoxin to cope with reactive sulfur species stress, mBio, 2022, 13(4).
Liu Daixi;Zhang Jiajie; Lü Chuanjuan; Xia Yongzhen; Liu Huaiwei; Jiao Nianzhi; Xun Luying; Liu Jihua*;Synechococcussp. strain PCC7002 uses sulfide:quinone oxidoreductase to detoxify exogenous sulfide and to convert endogenous sulfide to cellular sulfane sulfur, mBio, 2020, 11(1).
Liu Daixi;Song Hui; Li Yuanning; Huang Ranran; Liu Hongyue; Tang Kunxian; Jiao Nianzhi; Liu Jihua*; The transcriptional repressor PerR senses sulfane sulfur by Cysteine persulfidation at the structural Zn2+site inSynechococcussp. PCC7002, Antioxidants, 2023, 12(2) (423).
Liu Daixi#;Wang Yuwei#; Wei Lin; Ye Huahu; Liu Huan; Wang Ling; Liu Rui; Li Dongsheng; Lai Ren*; Snake venom-like waprin from the frog ofCeratophrys calcaratacontains antimicrobial function, Gene, 2012, 514(2): 99-104.
Huang Ranran; Wang Yafei;Liu Daixi; Wang Shaoyu; Lv Haibo; Yanzhen*; Long-read metagenomics of marine microbes reveals diversely expressed secondary metabolites, Microbiology Spectrum. 2023 Aug 17;11(4): e0150123.
Jinyu Chen;Daixi Liu; Yafei Wang; Shaoyu Wang; Ranran Huang; Effects of selective RNA processing and stabilization enzymes on carbon sequestration by photosynthesis ofSynechococcussp. PCC7002, Frontiers in Marine Science, 2023, 10(1223060)
Lü Chuanjuan; Xia Yongzhen;Liu Daixi;Zhao Rui; Gao Rui; Liu Honglei*; Xun Luying*;Cupriavidus necatorH16 uses favocytochrome c sulfide dehydrogenase to oxidize self-produced and added sulfide, Applied and Environmental Microbiology, 2017, 83(22): e01610-17.
五、承担课题
1.山东省自然科学基金青年项目，ZR2022QC044，2023.01-2025.12，15万，主持
2.中国博士后科学基金面上项目，2021M691913，2021.07-2023.07，8万，主持
3.国家重点研发计划，2020YFA0607604，2020.10-2025.10，39万，子子课题主持
4.青岛市应用项目资助，5万，主持
